CD300c Mouse anti-Human, PE, Clone: TX45, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 566126
The TX45 monoclonal antibody recognizes human CD300c which is also known as Leukocyte immunoglobulin-like receptor (LIR), CMRF35-like molecule 6 (CLM-6), or Immunoglobulin superfamily member 16 (IGSF16). CD300c is a type I transmembrane glycoprotein that belongs to the CMRF family within the Ig superfamily. CD300c is primarily expressed on myeloid cells and has also been detected on some T cells, B cells, NK cells, and other cell types. Amongst freshly-isolated leucocytes, the TX45 antibody only detects CD300c expressed on monocytes. CD300c is involved in the regulation of proinflammatory cytokine production by leucocytes.R-phycoerythrin (PE) is an accessory photosynthetic pigment found in red algae. It exists in vitro as a 240-kDa protein with 23 phycoerythrobilin chromophores per molecule. This makes PE one of the brightest fluorochromes for flow cytometry applications, but its photobleaching properties make it unsuitable for fluorescence microscopy.
|The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.|
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide.|
|LIR, IGSF16, CLM-6, CMRF-35, CMRF-35A, CMRF35-A1|
|Mouse IgG1, κ|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
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