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CD300c Mouse anti-Human, PE, Clone: TX45, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 566126

Catalog No. BDB566126

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The TX45 monoclonal antibody recognizes human CD300c which is also known as Leukocyte immunoglobulin-like receptor (LIR), CMRF35-like molecule 6 (CLM-6), or Immunoglobulin superfamily member 16 (IGSF16). CD300c is a type I transmembrane glycoprotein that belongs to the CMRF family within the Ig superfamily. CD300c is primarily expressed on myeloid cells and has also been detected on some T cells, B cells, NK cells, and other cell types. Amongst freshly-isolated leucocytes, the TX45 antibody only detects CD300c expressed on monocytes. CD300c is involved in the regulation of proinflammatory cytokine production by leucocytes.

R-phycoerythrin (PE) is an accessory photosynthetic pigment found in red algae. It exists in vitro as a 240-kDa protein with 23 phycoerythrobilin chromophores per molecule. This makes PE one of the brightest fluorochromes for flow cytometry applications, but its photobleaching properties make it unsuitable for fluorescence microscopy.


Affinity Purified
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
LIR, IGSF16, CLM-6, CMRF-35, CMRF-35A, CMRF35-A1
Mouse IgG1, κ
50 Tests
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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