CD31/PECAM-1 Mouse anti-Human, Primate, Rabbit, Alexa Fluor™ 350, Clone: C31.3 + JC/70A, Novus Biologicals™
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP234578AF350
DescriptionCD31/PECAM-1 Monoclonal antibody specifically detects CD31/PECAM-1 in Human,Primate,Rabbit samples. It is validated for Flow Cytometry,Immunohistochemistry,Immunocytochemistry,Immunofluorescence,Immunohistochemistry (Paraffin).
|C31.3 + JC/70A|
|Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin|
|adhesion molecule, CD31, CD31 antigen, CD31/EndoCAM, EndoCAM, FLJ34100, FLJ58394, GPIIA′, PECA1, PECAM-1, PECAM-1, CD31/EndoCAM, platelet endothelial cell adhesion molecule, platelet endothelial cell adhesion molecule-1, platelet/endothelial cell adhesion molecule|
|Human, Primate, Rabbit|
|Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)|
|Alexa Fluor 350|
|50 mM sodium borate with 0.05% sodium azide|
|This CD31/PECAM-1 Antibody (C31.3 + JC/70A) was developed against human recombinant CD31 protein (C31.3) & Membrane preparation of a spleen from a patient with hairy cell leukemia (JC/70A).|
|Store at 4°C in the dark.|
|CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 MAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.|
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