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CD31 Rat anti-Mouse, Alexa Fluor® 647, Clone: 390, Invitrogen™ Non-distribution product as customer accommodation.

Rat Monoclonal Antibody

Manufacturer:  Invitrogen A14716

Catalog No. 50-113-7629


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Description

Description

PECAM-1 (Platelet endothelial cell adhesion molecule), also known as cluster of differentiation 31 (CD31) is a protein that in human is encoded by the PECAM1 gene found on chromosome 17. PECAM1 is a member of the immunoglobulin (Ig) superfamily that is expressed on the surface of circulating platelets, monocytes, neutrophils, and particular T-cell subsets. Using a PCR-based analysis of somatic cell hybrids, Gumina et al. (1996) mapped PECAM1 to chromosome 17 in the region 17q23-qter. Several adhesion molecules expressed on platelets and endothelium also localized to 17q. Xie and Muller (1996) mapped the Pecam1 gene to mouse chromosome 6, region F3-G1, by fluorescence in situ hybridization. PECAM-1 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions, and PECAM-1 plays a key role in removing aged neutrophils from the body.
Specifications

Specifications

CD31
Monoclonal
0.5 mg/mL
PBS with 0.1% sodium azide
Q08481
CD31 antigen, CD31/EndoCAM, GPIIA′, PECA1, PECAM-1, CD31/EndoCAM, adhesion molecule, endoCAM, platelet endothelial cell adhesion molecule
Rat
IgG2a, kappa
25 μg
4° C
Primary
18613
Flow Cytometry
390
Alexa Fluor® 647
Pecam1
Liquid
Pecam1
Mouse leukocyte cell line 32D.
Purified
RUO
Antibody
Monoclonal
Mouse
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