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CD321 (F11R) Monoclonal Antibody (WK9), eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
$116.00 - $1372.00
Specifications
Antigen | CD321 (F11R) |
---|---|
Clone | WK9 |
Concentration | 0.5 mg/mL |
Classification | Monoclonal |
Conjugate | Unconjugated |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
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Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
14-932-137
|
LIFE TECHNOLOGIES
14932137 |
2 mg |
Each for $1,372.00
|
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14-932-180
|
LIFE TECHNOLOGIES
14932180 |
25 μg |
Each for $116.00
|
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Description
CD321 (F11R, JAM-1, JAM-A) is a cell-surface adhesion molecule belonging to the Ig superfamily of receptors. CD321 is a 32-41 kD glycoprotein, possessing two extracellular Ig-like domains, a transmembrane region, and a short cytosolic tail. The protein assembles at the membrane as a homodimer, and can associate laterally with other membrane proteins including integrins. CD321 is expressed on a variety of cell types, including leukocytes, platelets, erythrocytes, epithelial and endothelial cells, and plays a role in mediating cell-cell contact. CD321 can be found in close proximity to several components of epithelial tight junctions, including ZO-1 and occludin. CD321 is also involved in reovirus entry into cells.
CD321 (F11R, JAM-1, JAM-A) is a cell-surface adhesion molecule belonging to the Ig superfamily of receptors. CD321 is a 32-41 kD glycoprotein, possessing two extracellular Ig-like domains, a transmembrane region, and a short cytosolic tail. The protein assembles at the membrane as a homodimer, and can associate laterally with other membrane proteins including integrins. CD321 is expressed on a variety of cell types, including leukocytes, platelets, erythrocytes, stem cells, epithelial and endothelial cells, and plays a role in mediating cell-cell contact. CD321 can be found in close proximity to several components of epithelial tight junctions, including ZO-1 and occludin. CD321 is involved in the maintenance of epithelial and endothelial barriers, hematopoiesis, angiogenesis, and tumor proliferation, invasion, and metastasis.Specifications
CD321 (F11R) | |
0.5 mg/mL | |
Unconjugated | |
Mouse | |
Human | |
50848 | |
Primary | |
Antibody |
WK9 | |
Monoclonal | |
Liquid | |
RUO | |
Q9Y624 | |
IgG1 κ | |
Affinity chromatography | |
F11r |
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