Mouse anti-CD35, Clone: CR1/802, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP2446190.1MG
Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), ImmunofluorescenceCD35 Monoclonal antibody specifically detects CD35 in Human, Baboon, Monkey samples. It is validated for Flow Cytometry, Immunohistochemistry-Paraffin, Immunofluorescence.
|10mM PBS and 0.05% BSA with 0.05% Sodium Azide|
|Recombinant human CR1 protein|
|Protein A or G purified|
|Human, Baboon, Monkey|
|Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence|
|Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml|
|complement component (3b/4b) receptor 1 (Knops blood group), KN|
|Store at 4C.|
|Recognizes a protein of 210-220kDa, which is identified as the complement receptor 1 (CR1)/CD35. This MAb does not block CR1 activity. It is highly specific to CR1 and shows no cross-reaction with CR2. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This MAb labels follicular dendritic cells and follicular dendritic cell sarcoma.|
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