CD361 Mouse anti-Human, Alexa Fluor 647, Clone: MEM-216, BD
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 566328
The MEM-216 monoclonal antibody specifically binds to CD361. CD361 is a single-pass type I transmembrane glycoprotein that is encoded by EVI2B /(Ecotropic viral integration site 2B). EVI2B /is one of three genes within intron 27b of the neurofibromatosis type 1 ( NF1 /) gene. CD361 is expressed by T cells, B cells, NK cells, monocytes, granulocytes, and some dendritic cells including plasmacytoid dendritic cells. CD361 may be involved in keratinocyte and melanocyte differentiation and has been implicated in certain cancers including leukemias.Alexa Fluor™ 647 conjugates are highly photostable and remain fluorescent over a broad pH range. The excitation and emission maxima are nearly identical to those of APC. However, APC tends to be brighter while Alexa Fluor™ 647 is more optimal for intracellular applications. This fluorochrome exhibits uncommon photostability, making it an ideal choice for use in fluorescence microscopy. Due to nearly identical excitation and emission properties but different spillover characteristics, APC and Alexa Fluor™ 647 cannot be used simultaneously.
|Alexa Fluor 647|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
|Aqueous buffered solution containing BSA and ≤0.09% sodium azide.|
|EV12B, EVI-2B, D17S376, EVDB|
|Human Raji Cell Line|
|The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to Alexa Fluor™ 647 under optimum conditions, and unreacted Alexa Fluor™ 647 was removed.|
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