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Thermo Scientific™ Lab Vision™ CD37 Ab-1, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry, immunofluorescence and flow cytometry experiments with Thermo Scientific™ CD37 Ab-1, Mouse Monoclonal Antibody.

Specifications

Antigen CD37 Ab-1
Clone IPO-24
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (Frozen)
Classification Monoclonal
Conjugate Unconjugated
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Products 1
Catalog Number Mfr. No. Concentration Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Concentration Quantity Price Quantity & Availability  
MS541PABX
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Thermo Scientific™
MS541PABX
1mg/mL 200μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Ensure accurate, reproducible results in immunohistochemistry, immunofluorescence and flow cytometry experiments with Thermo Scientific™ CD37 Ab-1, Mouse Monoclonal Antibody.

CD37, a tetraspan transmembrane protein, is strongly expressed on normal and neoplastic mature (sIg+) B lymphocytes. In B-cell ontogeny, CD37 appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD37 is absent from platelets and erythrocytes. It associates with other tetraspan transmembrane proteins and MHC class II molecules to form a large complexes at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin lymphoma (B-NHL).

Host Species: Mouse

Clone: IPO-24

Isotype: IgG2b/κ

Species Reactivity: Human. Others not tested.

Epitope: Not determined

Immunogen: Spleen cells of a patient with hairy cell leukemia

Molecular Weight: 33-55 kDa

Positive Control: Raji cells, Tonsil or lymph node

Cellular Localization: Membrane

Recommended for:

  • Immunohistochemistry (Acetone-fixed frozen only)
  • Immunofluorescence
  • Flow Cytometry

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

CD37 Ab-1
Flow Cytometry, Immunofluorescence, Immunohistochemistry (Frozen)
Unconjugated
Murine
B-Cell
Spleen cells of a patient with hairy cell leukemia
IPO-24
Monoclonal
Concentrated
RUO
Primary
IgG2b kappa
SDS
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