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CD371 (Clec12A) Mouse anti-Human, PE, Clone: HB3, eBioscience™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen 12987841

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Catalog No. 50-112-2485


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Description

Description

Description: This HB3 monoclonal antibody reacts with human CD371, which is also known as Clec12A or Myeloid Inhibitory C-type Lectin-like receptor (MICL). CD371 is a highly glycosylated transmembrane receptor with a cytoplasmic ITIM that associates with SHP1 and SHP2. CD371 is expressed mainly on granulocytes, monocytes, macrophages, and dendritic cells, including plasmacytoid dendritic cells. Expression of CD371 on NK cells remains controversial. Although the function of CD371 is not fully understood, studies suggest that this receptor plays a role in inflammation and LPS activation. Applications Reported: This HB3 antibody has been reported for use in flow cytometric analysis. Applications Tested: This HB3 antibody has been pre-titrated and tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at 5 µL (0.125 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 µm post-manufacturing filtered.

CD371 is also known as Clec12A or Myeloid Inhibitory C-type Lectin-like receptor (MICL). CD371 is a highly glycosylated transmembrane receptor with a cytoplasmic ITIM that associates with SHP1 and SHP2. CD371 is expressed mainly on granulocytes, monocytes, macrophages, and dendritic cells, including plasmacytoid dendritic cells. Expression of CD371 on NK cells remains controversial. Although the function of CD371 is not fully understood, studies suggest that this receptor plays a role in inflammation and LPS activation.
Specifications

Specifications

CD371 (Clec12A)
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
Q5QGZ9
CLL-1, CLL1, DCAL-2, MICL, C-type lectin domain family 12 member A, C-type lectin protein CLL-1, C-type lectin superfamily, C-type lectin-like molecule-1, dendritic cell-associated lectin 2, myeloid inhibitory C-type lectin-like receptor
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
HB3
PE
CLEC12A
Liquid
CLEC12A
IgG1, kappa
25 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
160364
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