Epredia™ Lab Vision™ CD38 Ab-3, Mouse Monoclonal Antibody

Ensure accurate, reproducible results in immunohistochemistry experiments with Epredia™ CD38 Ab-3, Mouse Monoclonal Antibody.

Supplier:  Epredia™ MS983S0

Catalog No. MS983S0

Description

CD38 is a single chain type II integral transmembrane protein, which is highly expressed on thymocytes. It is also present on activated T cells and terminally differentiated B cells (plasma cells). Other reactive cells include NK cells, monocytes, macrophages, and dendritic cells. CD38 may be detected on cells from multiple myeloma, ALL (B and T) and some AML. It is, however, not found on most mature resting peripheral lymphocytes. CD38 functions as a multicatalytic ectoenzyme serving as ADP-ribosyl cyclase, cyclic ADP-ribose hydrolase and possibly NAD+ glycohydrolase or as a cell surface receptor. Antibodies to CD38 are useful in subtyping of lymphomas and leukemias, detection of plasma cells (i.e. identification of myelomas), and as a marker for activated B and T cells.

Host Species: Mouse

Clone: 38C03; same as SPC32

Isotype: IgG1

Species Reactivity: Human. Others not tested.

Epitope: Extracellular

Immunogen: Recombinant protein encoding the extracellular domain of human CD38

Molecular Weight: 45 kDa

Positive Control: Tonsil

Cellular Localization: Membrane

Recommended for:

• Immunohistochemistry (Formalin/paraffin)
• Western Blotting (Not suitable)

Note:

USA: RUO; Int'l: RUO

Specifications

• Antigen: CD38 Ab-3
• Classification: Monoclonal
• Conjugate: Unconjugated
• Immunogen: Recombinant protein encoding the extracellular domain of human CD38
• Quantity: 100 μL
• Research Discipline: Cell Adhesion
• Target Species: Human
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin)
• Clone: 38C03; same as SPC32
• Host Species: Mouse
• Purification Method: Tonsil
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Form: Concentrated