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CD38 Mouse anti-Human, PE-Texas Red®, Clone: HIT2, Invitrogen™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MHCD3817

Catalog No. 50-112-1403


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Description

Description

The R-phycoerythrin (PE)-Texas Red™ conjugate permits simultaneous multicolor labeling and detection of multiple targets with excitation by a single excitation source-the 488 nm line of the argon-ion laser.

CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein able to induce activation, proliferation and differentiation of mature lymphocytes and mediate apoptosis of myeloid and lymphoid progenitor cells. CD38 functions as a multi-catalytic ectoenzyme serving as ADP-ribosyl cyclase, cyclic ADP-ribose hydrolase and possibly NAD+ glycohydrolase or as a cell surface receptor. Antibodies to CD38 are useful in subtyping of lymphomas and leukemias, detection of plasma cells (i.e. identification of myelomas), and as a marker for activated B and T cells. CD38 participates in cell adhesion, signal transduction and calcium signaling. Further, CD38 is expressed at high levels in the pancreas, liver, kidney, maligt lymphoma and neuroblastoma. Diseases associated with CD38 dysfunction include chronic lymphocytic leukemia and Richter’s Syndrome.
Specifications

Specifications

CD38
Monoclonal
PE-Texas Red™
CD38
Liquid
CD38
Human CD38
Purified
ASR
Antibody
Monoclonal
Human
Flow Cytometry
HIT2
PBS with BSA, sucrose and 0.1% sodium azide
P28907
T10, ADP-ribosyl cyclase 1, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase, CD38 antigen p45, NAD+ nucleosidase, cADPr hydrolase 1, cyclic ADP-ribose hydrolase 1
Mouse
IgG1
0.5 mL
4° C, store in dark
Primary
952
Documents
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