CD4/CD26 Antibody Cocktail, FITC, PE, Invitrogen™

Antibody Cocktail

Supplier:  Thermo Scientific MA112119

Catalog No. 01-670-838

Description

This antibody is a monoclonal mixture of FITC-conjugated CD4 (clone 7E14, isotype IgG1) and PE-conjugated CD26 (clone EUG-6, isotype IgG2a).

The CD4 antigen is involved in the recognition of the type II MHC antigen. It is also a receptor for HIV. It is present on most T helper cells and normal thymocytes. The cytoplasmic portion of CD4 is associated with p56lck tyrosine kinase. CD4 expression is commonly found in human lymph nodes and tonsils. CD26 [also known as dipeptidyl peptidase IV (DPP IV), adenosine deaminase (ADA) binding protein]. 1 - 3 is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti CD3-induced IL - 2 production.

Specifications

• Antigen: CD4/CD26
• Classification: Cocktail
• Conjugate: PE
• Gene: DPP4
• Gene Alias: ADABP; ADCP2; ADCP-2; Adenosine deaminase complexing protein 2; CD26; CD4; CD4 antigen (p55); CD4 antigen p55; CD4 molecule; CD4 receptor; CD4mut; dipeptidyl peptidase 4; Dipeptidyl peptidase 4 membrane form; Dipeptidyl peptidase 4 soluble form; Dipeptidyl peptidase IV; Dipeptidyl peptidase IV membrane form; Dipeptidyl peptidase IV soluble form; dipeptidylpeptidase 4; dipeptidyl-peptidase 4; dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2); DPP IV; DPP4; DPPIV; DPP-IV; T-cell activation antigen CD26; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4; TP103
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 1803, 920
• Content And Storage: 4° C, store in dark, DO NOT FREEZE!
• Form: Liquid

• Applications: Flow Cytometry
• Clone: 7E14, EUG-6, EUG-6
• Formulation: PBS with 0.2% carrier protein and 0.08% sodium azide
• Gene Accession No.: P01730, P27487
• Gene Symbols: CD4, DPP4
• Immunogen: human peripheral blood T lymphocytes
• Quantity: 50 Tests
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1, IgG2a

Safety and Handling

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