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CD4 Mouse, anti-Human, R718, Clone: SK3, BD Horizon™
Mouse Monoclonal Antibody
Supplier: BD Biosciences 566930
Description
The SK3 monoclonal antibody specifically binds to CD4. The CD4 antigen is a 55 kDa type 1 transmembrane glycoprotein that belongs to the immunoglobulin superfamily. It is expressed on T-helper/inducer lymphocytes and monocytes. CD3+CD4+ T cells comprise approximately 28% to 58% of normal peripheral blood lymphocytes. CD4 is also expressed on 80% to 95% of normal thymocytes. The CD4 antigen is present in low density on the cell surface of monocytes and in the cytoplasm of monocytes and macrophages (CD3-CD4+). CD4 serves as a T cell coreceptor for MHC class II antigen recognition and as a receptor for the human immunodeficiency virus (HIV). The SK3 antibody inhibits HIV binding to CD4+ cells.
Specifications
| CD4 | |
| Monoclonal | |
| R718 | |
| 100 Tests | |
| Primary | |
| Refrigerate Upon Arrival |
| Flow Cytometry | |
| SK3 | |
| Mouse | |
| RUO | |
| Human | |
| Liquid |
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