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CD41/Integrin alpha 2b Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 245521AP

Catalog No. 50-173-4417


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Description

Description

CD41 (platelet glycoprotein IIb, ITGA2B) is composed of two subunits -120 kDa a, alpha and 23 kDa b, beta- that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. CD41 is also involved in blood coagulation by mediating platelet aggregation. Upon blood vessel damage, CD41 binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during the early stages of hematopoietic differentiation. Diseases associated with CD41 dysfunction include Glansmann Thrombasthenia, and Platelet type-16 bleeding disorder.
Specifications

Specifications

CD41/Integrin alpha 2b
0.45 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P08514, Q9QUM0
CD41, CD41B, GP2B, GPalpha IIb, GPIIb, GTA, HPA3, Integrin alpha IIb, ITGA2B, ITGAB
Rabbit
IgG
150 μL
-20°C
Primary
16399, 3674, 685269
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
ITGA2B
Liquid
Itga2b
CD41/Integrin alpha 2b Fusion Protein Ag19459
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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