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CD42d Armenian Hamster anti-Mouse, Rat, Clone: 1C2, eBioscience™ Non-distribution product as customer accommodation.

Armenian Hamster Monoclonal Antibody

$98.25 - $214.00

Specifications

Antigen CD42d
Clone 1C2
Target Species Mouse, Rat
Conjugate Unconjugated
Isotype IgG
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-125-70 Non-distribution product as customer accommodation.
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Invitrogen
14042180
25 μg
Each for $98.25
Add to cart
 
50-125-71 Non-distribution product as customer accommodation.
View Documents
Invitrogen
14042182
100 μg
Each for $214.00
Add to cart
 
Description

Description

Description: The monoclonal antibody 1C2 recognizes mouse and rat CD42d, a single transmembrane protein also known as platelet glycoprotein V (GPV). CD42d interacts with CD42a, CD42b and CD42c to form the receptor for von willebrand factor and thrombin. This functional complex plays a role in platelet adhesion. Expression of CD42d (unlike other markers such as CD41) is restricted to resting platelets and megakaryocytes and therefore is a good marker for development of megakaryocytes. Applications Reported: This 1C2 antibody has been reported for use in flow cytometric analysis, immunoprecipitation, and immunohistology staining of frozen tissue sections. Applications Tested: This 1C2 antibody has been tested by flow cytometric analysis of mouse platelets. This can be used at less than or equal to 0.25 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Purity: Greater than 90%, as determined by SDS-PAGE. Aggregation: Less than 10%, as determined by HPLC. Filtration: 0.2 µm post-manufacturing filtered.

Natural killer (NK) cells in teleosts and their evolutionary homologue are a subpopulation of lymphocytes with properties that distinguish them from either B- or T-cells. NK cells are important effectors of innate immunity where they release cytokines, which in turn up-regulate other immunological functions. Monoclonal antibodies have been used to identify different surface antigens present on NK cells. These surface antigens have not only been used to identify NK cells, but also their functionally distinct subsets. The Cluster of Differentiation (CD) nomenclature was established to standardize the naming of NK cells.
Specifications

Specifications

CD42d
Mouse, Rat
IgG
Monoclonal
Liquid
Antibody
4° C
1C2
Unconjugated
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation
Primary
Monoclonal
PBS with 0.09% sodium azide; pH 7.2
RUO
SDS

For Research Use Only.

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