Learn More
CD44 Std./H-CAM Ab-4 Mouse Monoclonal Antibody, Epredia™
Ensure accurate, reproducible results in immunohistochemistry, western blotting, immunoprecipitation and flow cytometry experiments.
Supplier: Epredia MS668P1
Description
CD44 is a cell surface glycoprotein expressed on lymphocytes, monocytes, and granulocytes. CD44 is also known as homing cell adhesion molecule (H-CAM), Phagocytic glycoprotein-1 (PgP-1), ECM-III, HUTCH-1, or Hermes-1. CD44 has been implicated in cell migration, in lymphocyte homing, and in tumor metastasis. Ab-4 reacts with red cells pretreated with 2-aminoethylisothiouronium bromide (AET). Digestion of intact erythrocytes by trypsin treatment leaves a 50-54 kDa protein fragment attached to the membrane, while chymotrypsin leaves a somewhat similarly sized 51-56 kDa component that are recognized by Ab-4. This antibody enhances IL-2 production by CD2-transfected murine hybridoma stimulated by JY cells while it has no significant effect on IL-2 production by Jurkat cells stimulated with CD3, PMA, or CD2. Ab-4 enhances proliferation of PBL stimulated with CD2.Host Species: Mouse
Clone: 156-3C11
Isotype: IgG2a
Species Reactivity: Human, Baboon and Green Monkey. Does not react with rat. Others not tested.
Epitope: Resistant to digestion by trypsin and chymotrypsin
Immunogen: Stimulated human leukocytes
Molecular Weight: 80-95 kDa
Positive Control: HUVEC or HeLa cells, tonsil or esophageal CA
Cellular Localization: Membrane
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
- Western Blotting
- Immunoprecipitation (Native verified)
- Flow Cytometry
Specifications
CD44 Std./H-CAM Ab-4 | |
Monoclonal | |
200μg/mL | |
Mouse | |
500 μL | |
Oncogenesis | |
Human, Non-human Primate | |
IgG2a |
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot | |
156-3C11 | |
Unconjugated | |
Stimulated human leukocytes | |
IVD | |
Primary | |
Concentrated |
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.