CD45RC Rat anti-Mouse, FITC, Clone: C455.1F, Invitrogen
Rat Monoclonal Antibody
Manufacturer: Invitrogen RMCD45RC01
DescriptionCD45RC (PTPRC) is a protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. It acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, the second affects the substrate specificity of the first. Upon T-cell activation, CD45RC recruits and dephosphorylates SKAP1 and FYN. Mutations of the gene can result in severe combined immunodeficiency and multiple sclerosis.
|PBS with 0.1% sodium azide|
|B220, CD45R, Cd45, Ly-5, Lyt-4, T200, cluster designation 45RC|
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