Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

CD46 Mouse anti-Human, Clone: 169-1-EA.3, Abnova™

Mouse monoclonal antibody raised against human CD46.

Manufacturer:  Abnova Corporation MAB12895

Catalog No. 89-933-839


Add to cart

Description

Description

The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. This gene is found in a cluster on chromosome 1q32 with other genes encoding structural components of the complement system. At least fourteen different transcript variants encoding fourteen different isoforms have been found for this gene. [provided by RefSeq]

Specifications

Specifications

CD46
169-1-EA.3
Mouse monoclonal antibody raised against human CD46.
In 50mM Na
MCP/MGC26544/MIC10/TLX/TRA2.10
Mouse
IgG2a
50 ug
Store at 4°C. Do not freeze. Open under aseptic conditions.
Monoclonal
Human
Flow Cytometry, Immunohistochemistry (PFA fixed), Western Blot
Unconjugated
Flow Cytometry Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) Western Blot The optimal working dilution should be determined by the end user.
Liquid
CD46
Human PBL and EBV transformed LCL.
Protein A purification
RUO
Primary
4179
SDS
Documents
Product Certifications
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit