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CD46 Mouse anti-Human, FITC, Clone: MEM-258, Invitrogen™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen A15745

Catalog No. 50-113-7744


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Description

Description

CD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.
Specifications

Specifications

CD46
Monoclonal
FITC
CD46
Liquid
CD46
Human CD46
Purified
RUO
Antibody
Monoclonal
Human
Flow Cytometry
MEM-258
PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
P15529
AHUS2, MCP, MGC26544, MIC10, TLX, TRA2.10
Mouse
IgG1
100 tests
4° C
Primary
4179
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