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CD49f (Integrin alpha 6) Rat anti-Human, Mouse, Biotin, Clone: eBioGoH3 (GoH3), eBioscience™ Non-distribution product as customer accommodation.

Rat Monoclonal Antibody

$97.50 - $228.00

Specifications

Antigen CD49f (Integrin alpha 6)
Clone eBioGoH3 (GoH3)
Target Species Human, Mouse
Conjugate Biotin
Isotype IgG2a, kappa
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-115-79 Non-distribution product as customer accommodation.
View Documents
Invitrogen
13049580
25 μg Each for $97.50
N/A
50-115-80 Non-distribution product as customer accommodation.
View Documents
Invitrogen
13049582
100 μg Each for $228.00
N/A
Description

Description

Description: The eBioGoH3 monoclonal antibody reacts with mouse and human CD49f, also known as integrin alpha 6, very late activation antigen 6 (VLA-6 alpha chain), and platelet gpIc. CD49f is a 120 kD transmembrane protein. CD49f associates with CD29, the integrin beta 1 chain, to form the VLA-6 complex; CD49f also associates with CD104, the integrin beta 4 chain, to form the alpha 6 beta 4 complex. CD49f is expressed primarily on T cells, monocytes, platelets, epithelial and endothelial cells. CD49f expression has also been found on germinal center B cells. The eBioGoH3 antibody is cross-reactive to integrin alpha 6 on human, mouse and bovine cells. This antibody has also been reported to have functional activity in blocking the binding of integrin alpha 6 to laminin. Applications Reported: This eBioGoH3 (GoH3) antibody has been reported for use in flow cytometric analysis, and immunohistology staining of frozen tissue sections. Applications Tested: This eBioGoH3 (GoH3) antibody has been tested by flow cytometric analysis of human peripheral blood cells. This can be used at less than or equal to 0.25 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Filtration: 0.

2 µm post-manufacturing filtered. The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene.
Specifications

Specifications

CD49f (Integrin alpha 6)
Human, Mouse
IgG2a, kappa
Monoclonal
Liquid
Antibody
4° C, store in dark, DO NOT FREEZE!
eBioGoH3 (GoH3)
Biotin
Flow Cytometry, Immunohistochemistry (Frozen)
Primary
Monoclonal
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
RUO

For Research Use Only.

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