CD5 Mouse anti-Human, Rat, Porcine, Bovine, Canine, Chicken, Several Species, Alexa Fluor™ 594, Clone: CD5/54/F6, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP234593AF594

Catalog No. NP23493A94

Description

CD5 Monoclonal antibody specifically detects CD5 in Human,Rat,Porcine,Bovine,Canine,Chicken,Equine,Guinea Pig,Monkey,Rabbit samples. It is validated for Western Blot,Flow Cytometry,ELISA,Immunohistochemistry,Immunocytochemistry,Immunofluorescence,Immunohistochemistry (Paraffin),Immunohistochemistry (Frozen).

Specifications

• Antigen: CD5
• Clone: CD5/54/F6
• Dilution: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
• Gene Alias: CD5 antigen, CD5 antigen (p56-62), CD5 molecule, LEU1T-cell surface glycoprotein CD5, Lymphocyte antigen T1/Leu-1, T1
• Host Species: Mouse
• Isotype: IgG1 Kappa
• Storage Requirements: Store at 4°C in the dark.
• Monoclonal or Polyclonal: Monoclonal
• Test Specificity: Recognizes a 67kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.

• Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Alexa Fluor™ 594
• Formulation: 50 mM sodium borate with 0.05% sodium azide
• Gene Symbols: CD5
• Immunogen: A synthetic peptide from the intracellular region of human CD5
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Gene ID (Entrez): 921
• Target Species: Bovine, Canine, Chicken, Equine, Guinea Pig, Human, Monkey, Porcine, Rabbit, Rat