CD51 Mouse anti-Human, PE, Clone: 13C2, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen A15458
DescriptionITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; ft.ITGB1 ft., ft.ITGB3 ft., ft.ITGB5 ft., ft.ITGB6 ft., and ft.ITGB8 ft.), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants.
|PBS with 0.1% sodium azide|
|CD51, MSK8, VNRA, antigen identified by monoclonal antibody L230, integrin alpha-V, vitronectin receptor subunit alpha, ITGAV|
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