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CD52 Mouse anti-Human, PerCP-eFluor™ 710, Clone: CF1D12, eBioscience™

Mouse Monoclonal Antibody

Manufacturer:  eBioscience 46052942

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Catalog No. 46-052-942



Description

Description

This CF1D12 monoclonal antibody reacts with human CD52, a cell surface glycoprotein expressed in the immune and reproductive systems. CF1D12 is thought to recognize the carbohydrate region of CD52, not the protein core of the molecule. Tissue-specific mod

Please protect this vial and stained samples from light. Fixation: Samples can be stored in IC Fixation Buffer (Product No. 00-8222-49) (100 µL of cell sample + 100 µL of IC Fixation Buffer) or 1-step Fix/Lyse Solution (Product No. 00-5333-57) for up to 3 days in the dark at 4°C with minimal impact on brightness and FRET efficiency/compensation. Some generalizations regarding fluorophore performance after fixation can be made, but clone specific performance should be determined empirically. Excitation: 488 nm; Emission: 710 nm; Laser: Blue Laser Human CD52, also known as Cambridge pathology antigen 1 (CAMPATH-1), is a glycoprotein found in the male reproductive tract and immune cells. It is abundantly expressed on the surface of nearly all human peripheral blood lymphocytes. The CD52 antigen is GPI-anchored membrane receptor that consists of a small 12 amino acid peptide attached to a large N-linked carbohydrate group. CD52 is a potent target for inducing cytolysis of mature lymphocytes. Alemtuzumab, a humanized monoclonal antibody targeting CD52, is used as an immunomodulatory drug for the treatment of chronic lymphocytic leukemia, T cell lymphomas, multiple sclerosis, and other diseases.
Specifications

Specifications

CD52
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
P31358
Cambridge pathology 1 antigen; CAMPATH-1 antigen; CDW52; Epididymal secretory protein E5; epididymis secretory sperm binding protein Li 171mP; He5; HEL-S-171mP; Human epididymis-specific protein 5
Mouse
IgG3, kappa
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
1043
Flow Cytometry
CF1D12
PerCP-eFluor™ 710
CD52
Liquid
CD52
Human CD52
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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