CD53 Mouse anti-Human, PE, Clone: MEM-53, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen A15769
DescriptionCD53 is a tetraspanin family transmembrane glycoprotein expressed in the lymphoid-myeloid lineage. This molecule has been reported to form complexes with other leukocyte surface proteins such as CD2, CD19, CD21, MHC II, VLA-4 or tetraspanins CD37, CD81 and CD82, thus probably modulating various signaling processes. CD53 is involved in radioresistancy of tumour cells and its triggering has anti-apoptotic effect. In thymus, CD53 is up-regulated in response to positive selection signals during T cell development, and is strongly expressed upon macrophage exposure to bacterial lipopolysaccharide, whereas stimulation of neutrophils results in down-regulation of CD53 expression.
|PBS with 0.2% BSA and 15mM sodium azide|
|MOX44, TSPAN25, CD53 antigen, CD53 glycoprotein, CD53 tetraspan antigen|
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