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CD53 Mouse anti-Human, PE, Clone: MEM-53, Invitrogen™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen A15769

Catalog No. 50-113-7100


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Description

Description

CD53 is a tetraspanin family transmembrane glycoprotein expressed in the lymphoid-myeloid lineage. This molecule has been reported to form complexes with other leukocyte surface proteins such as CD2, CD19, CD21, MHC II, VLA-4 or tetraspanins CD37, CD81 and CD82, thus probably modulating various signaling processes. CD53 is involved in radioresistancy of tumour cells and its triggering has anti-apoptotic effect. In thymus, CD53 is up-regulated in response to positive selection signals during T cell development, and is strongly expressed upon macrophage exposure to bacterial lipopolysaccharide, whereas stimulation of neutrophils results in down-regulation of CD53 expression.
Specifications

Specifications

CD53, CD53
Monoclonal
PE
CD53
Liquid
CD53
Human CD53
Purified
RUO
Antibody
Monoclonal
Human
Flow Cytometry
MEM-53
PBS with 0.2% BSA and 15mM sodium azide
P19397
MOX44, TSPAN25, CD53 antigen, CD53 glycoprotein, CD53 tetraspan antigen
Mouse
IgG1
100 tests
4° C
Primary
963
Documents
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