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CD53 Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA551130

Catalog No. PA551130


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Description

Description

CD53 / TSPAN-25 Polyclonal Antibody detects endogenous levels of CD53 / TSPAN-25 protein.

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Specifications

Specifications

CD53
Polyclonal
Unconjugated
CD53
Liquid
CD53
Synthesized peptide derived from the Internal region of human CD53.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
ELISA, Western Blot
1 mg/mL
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
P19397, Q61451, P24485
MOX44, TSPAN25, CD53, Tetraspanin-25, CD53 glycoprotein, Cell surface glycoprotein CD53, Leukocyte surface antigen CD53
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
12508, 24251, 963
Documents
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