CD6 Monoclonal Antibody (MEM-98), PE, Invitrogen™

Mouse Monoclonal Antibody

Supplier:  Thermo Scientific MA110258

Catalog No. PIMA110258

Description

CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL). CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse. CD6-ALCAM mediated cell adhesion is also important for T cell proliferation. CD6 may exert some its functions via association with CD5, probably by fine-tuning CD5 signaling. Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells.

Specifications

• Antigen: CD6
• Classification: Monoclonal
• Conjugate: PE
• Gene Accession No.: P30203
• Gene Symbols: CD6
• Immunogen: Human CD6 antigen purified by immunoaffinity chromatography from HBP-ALL cells followed by preparative SDS-PAGE of non-boiled non-reduced sample (excised piece of gel corresponding to the 100 kDa zone).
• Quantity: 100 Tests
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry
• Clone: MEM-98
• Gene: CD6
• Gene Alias: FLJ44171, TP120, CD6 antigen, T-cell differentiation antigen CD6, T12
• Host Species: Mouse
• Purification Method: Purified
• Regulatory Status: RUO
• Gene ID (Entrez): 923
• Content And Storage: 4° C, store in dark, DO NOT FREEZE!
• Form: Liquid