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CD6 Monoclonal Antibody (MEM-98), PE, Invitrogen™
Mouse Monoclonal Antibody
Supplier: Thermo Scientific MA110258
SDSDocumentsProduct Certifications Promotions
DescriptionCD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL). CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse. CD6-ALCAM mediated cell adhesion is also important for T cell proliferation. CD6 may exert some its functions via association with CD5, probably by fine-tuning CD5 signaling. Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells.
|Human CD6 antigen purified by immunoaffinity chromatography from HBP-ALL cells followed by preparative SDS-PAGE of non-boiled non-reduced sample (excised piece of gel corresponding to the 100 kDa zone).|
|FLJ44171, TP120, CD6 antigen, T-cell differentiation antigen CD6, T12|
|4° C, store in dark, DO NOT FREEZE!|
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