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CD68 Mouse anti-Human, Biotin, Clone: 815CU17, eBioscience™ Invitrogen™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Catalog No. 13-068-782


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Description

Description

This 815CU17 MAb reacts with human CD68, a 110 kDa, transmembrane glycoprotein that belongs to the sialomucin family and is closely related to the lysosomal-associated membrane proteins (LAMP) and scavenger receptor. CD68 is predominantly an intracellular protein, found mainly in the late endosomal compartment but can be detected in smaller amounts on the surface of mainly myeloid-derived cells: monocytes, macrophages, dendritic cells (and in some langerhans cells), neutrophils, basophils, mast cells, myeloid progenitor cells, and a subset of CD34+ hematopoietic bone marrow progenitor cells. The function has not been fully elucidated but based on homology and structure, CD68 may play a role in antigen processing or presentation and protection of the lysosomal membrane from hydrolytic enzymes. Reports have also shown expression in activated T cells, and about 40% of peripheral blood B lymphocytes and 50% of all B-ALL. This 815CU17 antibody does not cross-react with mouse or rat CD68. For flow cytometric analysis of human CD68, we recommend clone eBioY1/82A.

CD68 Monoclonal antibody specifically detects CD68 in Human samples. It is validated for Immunohistochemistry (Paraffin), Western Blot
Specifications

Specifications

Liquid
Immunohistochemistry (Paraffin), Western Blot
815CU17
Biotin
Cd68
CD68; CD68 antigen; CD68 molecule; Gp110; LAMP4; macrophage antigen CD68; macrosialin; SCARD1; scavenger receptor class D, member 1; similar to CD68 antigen
IgG1, kappa
100 μg
4° C, store in dark, DO NOT FREEZE!
Primary
968
CD68
Monoclonal
0.5 mg/mL
PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2
P34810
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
SDS
Documents
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