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CD7 Mouse anti-Human, Clone: OTI1A6, liquid, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner TA506337

Catalog No. 50-167-6576


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Description

Description

CD7 (gp40, Leu9) is a 40 kDa member of the immunoglobulin gene superfamily. CD7 contains N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxy-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. Further, CD7 is also found on natural killer cells, a small subpopulation of normal B cells and on maligt B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3 ft.-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation. Expression of CD7 is an important marker used in leukemia diagnostics.
Specifications

Specifications

CD7
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
P09564
GP40, LEU-9, TP41, Tp40
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
924
Immunohistochemistry (Paraffin), Western Blot
OTI1A6
Unconjugated
CD7
Liquid
CD7
Full length human recombit protein of human CD7 produced in HEK293T cell.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
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