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Transferrin Receptor Mouse anti-Human, FITC, Clone: T56/14, Invitrogen™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MHCD7101

Catalog No. 50-112-1232


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Description

Description

Commonly used, FITC conjugates provide relatively high absorptivity, excellent fluorescence quantum yield, and good water solubility.

CD71 (transferrin receptor) is a type II transmembrane glycoprotein expressed as homodimer in erythroid blood cell line and in activated leukocytes. Upon binding of holotransferrin (complex of transferrin and iron ions), CD71 is internalized by clathrin-mediated endocytosis. Acidification of endosomes by vesicular membrane proton pumps leads to dissociation of iron ions, whereas transferrin (apotransferrin) remains associated with CD71 and recycles to the cell surface, where it is released upon exposure to normal pH. CD71 is also involved in uptake of non-transferrin bound iron.
Specifications

Specifications

CD71
Monoclonal
FITC
TFRC
Liquid
TFRC
Human CD71
Purified
ASR
Antibody
Monoclonal
Human
Flow Cytometry
T56/14
PBS with 4mg/mL BSA and 0.1% sodium azide
P02786
CD71, T9, TFR, TFR1, TR, TRFR, p90, transferrin receptor protein 1
Mouse
IgG1
0.5 mL
4° C, store in dark
Primary
7037
Documents
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