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CD79b Mouse, anti-Human, R718, Clone: 3A2-2E7, BD OptiBuild™

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 751985

Catalog No. BDB751985


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Description

Description

The 3A2-2E7 monoclonal antibody (also known as SN8) specifically recognizes CD79b. Immunoglobulin (Ig) antigen receptors are composed of a non-covalently-associated complex of Ig and two other proteins, Igα and Igβ, clustered as CD79a and CD79b, respectively. CD79b is a membrane glycoprotein of 229 residues, with a predicted relative molecular mass of 36-40 kDa. Its expression is restricted to B lineage cells. CD79b reportedly associates with surface IgM and is involved in signal transduction. The 3A2-2E7 antibody has similar reactivity characteristics as clone CB3-1. The 3A2-2E7 and CD3-1 antibodies specifically react with an epitope that is enhanced on certain B-cell leukemias such as prolymphocytic leukemia and lymphoma, but not on chronic lymphocytic leukemia.

Specifications

Specifications

CD79b
3A2-2E7
Liquid
50 μg
Refrigerate Upon Arrival
Monoclonal
Flow Cytometry
R718
Mouse
RUO
Primary
Human
SDS
Documents
Product Certifications
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