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CD8, Mouse anti-Human, PE, Clone: SFCI21Thy2D3 (T8), Beckman Coulter™

Mouse Monoclonal Antibody

$441.66 - $746.64

Specifications

Host Species Murine
Conjugate PE
Isotype IgG1
Antigen CD8
Monoclonal or Polyclonal Monoclonal
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
CO6603274 View Documents Coulter Corporation
6603274
100 Tests Each for $746.64
Add to cart
 
CO6603848 View Documents Coulter Corporation
6603848
50 Tests Each for $441.66
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Description

Description

The CD8 antigen is a disulfide-linked dimer, which exists either as a CD8α homodimer or as a CD8α/β heterodimer. CD8α is required for surface expression of CD8β. The molecular weight of each monomer of α or β is approximately 32-34 kDa. CD8 binds to a non-polymorphic domain (α3 domain) of MHC Class I molecules. CD8 is expressed on a subset of human peripheral blood T lymphocytes. A subset of NK cells possess the CD8 antigen but show low to medium density of expression. CD8α homodimer is expressed by NK cells and γ/δ+ T cells. CD8 is also present on most thymocytes where it is frequently co-expressed with CD4, and on a subpopulation of bone marrow cells. The CD8 molecule acts with the T Cell Receptor (TCR) as a coreceptor for MHC class I restricted antigen recognition. CD8 is widely used as a marker of cytotoxic T lymphocytes.
Specifications

Specifications

Murine
IgG1
Monoclonal
Primary
PE
CD8
Purified
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