Thermo Scientific Lab Vision CD8, Rabbit Polyclonal Antibody
Ensure accurate and reproducible results in immunohistochemistry experiments with Thermo Scientific CD8, Rabbit Polyclonal Antibody.
Manufacturer: Thermo Scientific RB9009P1
Ensure accurate and reproducible results in immunohistochemistry experiments with Thermo Scientific CD8, Rabbit Polyclonal Antibody, one marker in a comprehensive antibody portfolio that addresses all major disease states, ensuring the ideal tests are always available.CD8 molecule consists of two chains, termed alpha and Beta chain, which are expressed as a disulphide-linked alpha/Beta heterdimer or as an alpha/alpha homodimer on T cell subset, thymocytes and NK cells. The majority of CD8+ T cells express CD8 as alpha/Beta heterdimer. CD8 functions as a coreceptor in concert with TCR for binding the MHC class I/peptide complex. The HIV-2 envelope glycoprotein binds CD8 alpha chain (but not Beta chain).
Host Species: Rabbit
Species Reactivity: Human. Others not tested.
Immunogen: Synthetic peptide sequence comprising the 13 C-terminal amino acids of the cytoplasmic domain of α-chain of the CD8 molecule
Positive Control: Tonsil
Cellular Localization: Membrane
- Immunohistochemistry (Formalin/paraffin)
|Synthetic peptide sequence comprising the 13 C-terminal amino acids of the cytoplasmic domain of alpha chain of the CD8 molecule|
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