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CD80 Rat anti-Mouse, FITC, Clone: 1G10, Invitrogen™ Non-distribution product as customer accommodation.

Rat Monoclonal Antibody

Manufacturer:  Invitrogen A14722

Catalog No. 50-113-6951


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Description

Description

CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.
Specifications

Specifications

CD80
Monoclonal
0.5 mg/mL
PBS with 0.1% sodium azide
Q00609
B7-1, B7.1, Cd28l, Ly-53, Ly53, MIC17, TS/A-1, LAB7, B7.1, CD28LG, CD28LG1
Rat
IgG2a
25 μg
4° C
Primary
12519
Flow Cytometry
1G10
FITC
Cd80
Liquid
Cd80
Dibutyryl cAMP-Activated 5C2 cells
Purified
RUO
Antibody
Monoclonal
Mouse
Documents
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