CD80 Monoclonal Antibody (16-10A1), Invitrogen™

Armenian Hamster Monoclonal Antibody

Supplier:  Thermo Scientific MA110287

Catalog No. PIMA110287

Description

CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.

Specifications

• Antigen: CD80
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Gene: Cd80
• Gene Alias: B7-1, B7.1, Cd28l, Ly-53, Ly53, MIC17, TS/A-1, LAB7, B7.1, CD28LG, CD28LG1
• Host Species: Armenian Hamster
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 12519, 403765
• Content And Storage: 4° C, do not freeze
• Form: Liquid

• Applications: Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Immunoprecipitation
• Clone: 16-10A1
• Conjugate: Unconjugated
• Gene Accession No.: Q00609
• Gene Symbols: CD80
• Immunogen: CD80-transfected CHO cell line
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Canine, Mouse
• Product Type: Antibody
• Isotype: IgG2