CD81 Antibody (1.3.3.22), PE/Cy7, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP254548PECY7

Catalog No. N254548PEC7

Description

CD81 Monoclonal specifically detects CD81 in Human, Mouse, Rat samples. It is validated for Flow Cytometry, Flow (Cell Surface), Knockout Validated.

Specifications

• Antigen: CD81
• Classification: Monoclonal
• Conjugate: PE-Cyanine7
• Formulation: PBS with 0.05% Sodium Azide
• Gene Symbols: CD81
• Immunogen: Recombinant full-length human CD81 protein (Uniprot: P60033)
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: Recognizes a protein of 26kDa, identified as CD81 (Workshop VI; Code CD81.1)). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.
• Content And Storage: Store at 4°C in the dark. Do not freeze.

• Applications: Flow Cytometry, Immunoassay
• Clone: 1.3.3.22
• Dilution: Flow Cytometry, Flow (Cell Surface), Knockout Validated
• Gene Alias: CD81 antigen, CD81 antigen (target of antiproliferative 1), CD81 molecule, CVID6, TAPA1, TAPA-1, Target of the antiproliferative 1, Tetraspanin-28, Tspan-28, tspan-28,26 kDa cell surface protein TAPA-1, TSPAN28S5.7
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Research Discipline: Adaptive Immunity, Cell Cycle and Replication, Immunology
• Gene ID (Entrez): 975.0
• Target Species: Human, Mouse, Rat
• Isotype: IgG1 κ