CD86 Mouse anti-Human, Clone: SPM600, Abnova™
Mouse monoclonal antibody raised against full length recombinant human CD86.
Manufacturer: Abnova Corporation MAB13183
This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined. [provided by RefSeq]
|Mouse monoclonal antibody raised against full length recombinant human CD86.|
|In 10mM PBS (0.05% BSA, 0.05% sodium azide).|
|Store at 4°C.|
|Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot|
|Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2-4 ug/mL) Western Blot (0.5-1 ug/mL) The optimal working dilution should be determ|
|Recombinant protein corresponding to full length human CD86.|
|Protein A/G purification|
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