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CD8 alpha Rat anti-Mouse, Pacific Blue™, Clone: 5H10, Invitrogen™ Non-distribution product as customer accommodation.

Rat Monoclonal Antibody

$123.00 - $303.00

Specifications

Antigen CD8 alpha
Clone 5H10
Target Species Mouse
Conjugate Pacific Blue™
Isotype IgG2b
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-113-8101 Non-distribution product as customer accommodation. Available on GSA/VA Contract for Federal Government customers only. View Documents Invitrogen
MCD0828
1 mL Each for $303.00
Add to cart
 
50-113-8102 Non-distribution product as customer accommodation. View Documents Invitrogen
MCD0828TR
25 tests Each for $123.00
Add to cart
 
Description

Description

CD8 (Cluster of Differentiation 8) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediate efficient cell-cell interactions within the immune system. The CD8 antigen acts as a co-receptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. CD8 is found on a T cell subset of normal cytotoxic/suppressor cells which make up approximately 20-35 % of human peripheral blood lymphocytes. The CD8 antigen is also detected on natural killer (NK) cells, subpopulations of peripheral blood null cells, thymocytes and bone marrow cells. The CD8 co-receptor functions as either a homodimer composed of two alpha chains, or as a disulfide-linked heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. The majority of CD8+ T cells express CD8 as a alpha/beta heterodimer. In HIV, the HIV-2 envelope glycoprotein binds CD8 alpha chain (but not the beta chain).

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Specifications

Specifications

CD8 alpha
Mouse
IgG2b
Monoclonal
Liquid
Antibody
4° C
5H10
Pacific Blue™
Flow Cytometry
Primary
Monoclonal
PBS with BSA and 0.1% sodium azide
RUO
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