Invitrogen™ Cdc23 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5117855

Catalog No. PIPA5117855

Description

Cdc23 Polyclonal Antibody for Western Blot, IP

Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). Ubr2 (Ubiquitin-protein ligase E3-alpha-2), also known as N-recognin-2, is a 1755 amino acid protein that contains one UBR-type zinc finger and one RING-type zinc finger. Participating in protein modification events within the N-end rule pathway, Ubr2 functions as an E3 ubiquitin-protein ligase that recognizes and binds proteins that contain destabilizing N-terminal residues, thereby leading to their ubiquitination and subsequent degradation. Mice lacking Ubr2 are infertile due to defects in male meiosis.

Specifications

• Antigen: Cdc23
• Classification: Polyclonal
• Formulation: PBS with 0.03% ProClin 300; pH 7
• Gene Accession No.: Q9UJX2
• Gene Symbols: Cdc23
• Immunogen: E. coli-derived Human CDC23 fragment.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Gene: Cdc23
• Gene Alias: 6030435O18; ANAPC8; anaphase promoting complex subunit 8; anaphase-promoting complex subunit 8; APC8; CDC23; CDC23 (cell division cycle 23, yeast, homolog); CDC23 cell division cycle 23; cell division cycle 23; cell division cycle 23 homolog; cell division cycle protein 23; cell division cycle protein 23 homolog; CUT23; cyclosome subunit 8; D18Ertd243e; zgc:56013
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 8697
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov