Invitrogen™ Cdc45L Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA522027

Catalog No. PIPA522027

Description

Recommended positive controls: H1299. Predicted reactivity: Mouse (93%), Rat (92%), Bovine (90%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple polyadenylation sites of this gene are reported.

Specifications

• Antigen: Cdc45L
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cdc45
• Gene Alias: CDC 45; CDC 45L; Cdc45; CDC45 cell division cycle 45 homolog; CDC45 like; CDC45L; CDC45L2; CDC45-related protein; Cell division control protein 45 homolog; cell division cycle 45; cell division cycle 45 homolog; cell division cycle 45-like 2; human CDC45; PORC PI 1; PORC-PI-1; UNQ374/PRO710
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8318
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: O75419
• Gene Symbols: Cdc45
• Immunogen: Recombinant fragment corresponding to a region within amino acids 298 and 566 of CDC45L (Uniprot ID#O75419).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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