Invitrogen™ CDC6 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA5142565

Catalog No. PIPA5142565

Description

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.

Specifications

• Antigen: CDC6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CDC6
• Gene Alias: CDC18(S.pombe); CDC18L; cdc18-related protein; CDC6; CDC6 cell division cycle 6 homolog; CDC6-related protein; Cell division control protein 6 homolog; cell division cycle 6; cell division cycle 6 homolog; HsCDC18; HsCDC6; p62(cdc6)
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 990
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q99741
• Gene Symbols: CDC6
• Immunogen: Peptide with sequence RKSQEITTNSEQRCP.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG