Invitrogen™ CDH18 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA536240

Catalog No. PIPA536240

Description

This antibody detects endogenous protein at a molecular weight of 88 kDa. Purity is >95% by SDS-PAGE.

This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance. Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

Specifications

• Antigen: CDH18
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CDH18
• Gene Alias: B230220E17Rik; Cadherin; Cadherin 14; cadherin 18; cadherin 18, type 2; Cadherin14; cadherin-14; Cadherin18; Cadherin-18; cadherin-like 24; CDH14; Cdh14l; CDH18; CDH24; ey-cadherin
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1016, 310174, 320865
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q13634
• Gene Symbols: CDH18
• Immunogen: Synthetic peptide corresponding to amino acids 96-140 of human Cadherin-18.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG