CDK8 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 220671AP
DescriptionCDK8 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the ft.Mediator-like ft. protein complexes and the basal transcription machinery.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|CDK8, Cell division protein kinase 8, cyclin dependent kinase 8, K35, Mediator complex subunit CDK8, Protein kinase K35|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|CDK8 Fusion Protein Ag17148|
|Antigen Affinity Chromatography|
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