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CDK8 Rabbit anti-Human, Mouse, Unconjugated, Polyclonal, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer:  Active MotifSupplier Diversity Partner 61482

Encompass

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Catalog No. 50-199-3435


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Description

Description

A family of proteins designated as cdks are critical regulators of cell cycle progression. The prototype member of this family, p34/Cdc 2, and a related protein Cdk 2, function late in the cycle while Cdk 4 and Cdk 6 are critically involved in G1 to S progression. The p54/Cdk 8 interacts exclusively with Cyclin C. The Cdk 8 Cyclin C complex activates the kinase. Because of analogy with yeast Cdk 8, it has been proposed that the human Cdk 8 Cyclin C may interact with RNA polymerase, thus influencing the transcription mechanism(s) that lead to cell division.
Specifications

Specifications

CDK8
ChIP assay, ChIP-sequencing, Western Blot
Unconjugated
Cdk8
Liquid
Rabbit
IgG
10 μL
-20°C, Avoid Freeze/Thaw Cycles
Primary
1024, 264064
Cdk8
Lot-Specific
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
P49336, Q8R3L8
Cdk8; CDK8 protein kinase; Cell division protein kinase 8; cyclin dependent kinase 8; Cyclin-dependent kinase 8; K35; Mediator complex subunit CDK8; Mediator of RNA polymerase II transcription subunit CDK8; MGC126074; MGC126075; Protein kinase K35; RGD1560888; wu:fk95h11
This antibody was raised against a peptide within the C-terminal region of human CDk8.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
SDS
Documents
Product Certifications
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