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Tocris Bioscience™ CDN 1163
SERCA2 allosteric activator
Supplier: Tocris Bioscience™ 5869/50
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Description
CDN 1163 is a SERCA2 allosteric activator. Increases Ca2+-ATPase activity and Ca2+ uptake by ER microsomes from obese mice. Rescues HEK cells from ER stress-induced cell death. Reduces fasting glucose levels and adipose tissue weight, and increases energy expenditure in ob/ob mice. Also improves glucose tolerance and reverses hepatic steatosis in ob/ob mice. Neuroprotective and improves memory and cognition in a mouse Alzheimer's disease model. Orally bioavailable.Specifications
4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide | |
50 mg | |
C20H20N2O2 | |
>98% |
892711-75-0 | |
Ca2+-ATPase Activators | |
320.38 |
Safety and Handling
Recommended Storage : Store at Room Temperature
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