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Tocris Bioscience™ CDN 1163

SERCA2 allosteric activator

Supplier:  Tocris Bioscience™ 5869/50

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Catalog No. 58-695-0


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Description

Description

CDN 1163 is a SERCA2 allosteric activator. Increases Ca2+-ATPase activity and Ca2+ uptake by ER microsomes from obese mice. Rescues HEK cells from ER stress-induced cell death. Reduces fasting glucose levels and adipose tissue weight, and increases energy expenditure in ob/ob mice. Also improves glucose tolerance and reverses hepatic steatosis in ob/ob mice. Neuroprotective and improves memory and cognition in a mouse Alzheimer's disease model. Orally bioavailable.
Specifications

Specifications

4-(1-Methylethoxy)-N-(2-methyl-8-quinolinyl)benzamide
50 mg
C20H20N2O2
>98%
892711-75-0
Ca2+-ATPase Activators
320.38
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Safety and Handling

Recommended Storage : Store at Room Temperature

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