CDX2, Mouse anti-Human, Alexa Fluor 488, Clone: UPK1A/2923, Novus Biologicals™
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP275759AF488
DescriptionCDX2 Monoclonal antibody specifically detects CDX2 in Human samples. It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin).
|Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin|
|50mM Sodium Borate with 0.05% Sodium Azide|
|Recombinant full-length human CDX2protein|
|Protein A or G purified|
|Store at 4°C in the dark.|
|The specificity of this monoclonal antibody to its intended target was validated by HuProt Human Proteome Microarray, containing more than 19,000, full-length human proteins. The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.|
|Western Blot,Immunohistochemistry,Immunohistochemistry (Paraffin)|
|Alexa Fluor 488|
|caudal type homeo box transcription factor 2, caudal type homeobox 2, Caudal-type homeobox protein 2, CDX-3, CDX3caudal type homeobox transcription factor 2, homeobox protein CDX-2|
|Cancer, Chromatin Research, DNA Repair, Growth and Development, Transcription Factors and Regulators|
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