CDX2, Mouse anti-Human, DyLight 680, Clone: UPK1A/2923, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP275759FR

Catalog No. NB008929

Description

CDX2 Monoclonal antibody specifically detects CDX2 in Human samples. It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin).

Specifications

• Antigen: CDX2
• Clone: UPK1A/2923
• Dilution: Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
• Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
• Gene Symbols: CDX2
• Immunogen: Recombinant full-length human CDX2protein
• Monoclonal or Polyclonal: Monoclonal
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Storage Requirements: Store at 4°C in the dark.
• Test Specificity: The specificity of this monoclonal antibody to its intended target was validated by HuProt Human Proteome Microarray, containing more than 19,000, full-length human proteins. The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.

• Applications: Western Blot,Immunohistochemistry,Immunohistochemistry (Paraffin)
• Conjugate: DyLight 680
• Format: Purified,Conjugated
• Gene Alias: caudal type homeo box transcription factor 2, caudal type homeobox 2, Caudal-type homeobox protein 2, CDX-3, CDX3caudal type homeobox transcription factor 2, homeobox protein CDX-2
• Host Species: Mouse
• Isotype: IgG1
• Primary or Secondary: Primary
• Quantity: 0.1 mL
• Research Discipline: Cancer, Chromatin Research, DNA Repair, Growth and Development, Transcription Factors and Regulators
• Target Species: Human