CDX2 Mouse anti-Human, Janelia Fluor 646, Clone: PCRP-CDX2-1A3, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP275759JF646

Catalog No. NB008934

Description

CDX2 Monoclonal specifically detects CDX2 in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: CDX2
• Classification: Monoclonal
• Conjugate: Janelia Fluor 646
• Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
• Gene Symbols: CDX2
• Immunogen: Recombinant human full-length CDX2 protein (Uniprot: Q99626)
• Quantity: 0.1 mL
• Research Discipline: Cancer, Chromatin Research, DNA Repair, Growth and Development, Transcription Factors and Regulators
• Test Specificity: The specificity of this monoclonal antibody to its intended target was validated by HuProtTMArray, containing more than 19,000, full-length human proteins. The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.
• Content And Storage: Store at 4°C in the dark.

• Applications: Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)
• Clone: PCRP-CDX2-1A3
• Dilution: Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
• Gene Alias: caudal type homeo box transcription factor 2, caudal type homeobox 2, Caudal-type homeobox protein 2, CDX-3, CDX3caudal type homeobox transcription factor 2, homeobox protein CDX-2
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Isotype: IgG1 κ