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CEACAM-5/CD66e Mouse anti-Human, Clone: COL-1 + CEA31 + C66/261, Novus Biologicals™
Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP2342330.02MG
SDSDocumentsProduct Certifications Promotions
DescriptionCEACAM5/CD66e Monoclonal specifically detects CEACAM5/CD66e in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.
|PBS with 0.05% BSA. with 0.05% Sodium Azide|
|Carcinoembryonic antigen, carcinoembryonic antigen-related cell adhesion molecule 5, CD66e antigen, CEACD66e, DKFZp781M2392, Meconium antigen 100|
|Protein A purified|
|This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.|
|Store at 4C.|
|IgG2a, IgG1 κ|
|Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)|
|COL-1 + CEA31 + C66/261|
|Western Blot 0.25-0.5ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein, Immunohistochemistry-Paraffin 1-2ug/ml, Immunohistochemistry-Frozen 1-2ug/ml|
|Human colon carcinoma extract (COL-1 & CEA31); CEA recombinant protein (C66/261)|
|Cancer, Cellular Markers, Immunology|
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