Cefoperazone sodium salt, Thermo Scientific Chemicals

Description

Cefoperazone sodium salt, CAS # 62893-20-3, is the sodium salt form of cefoperazone. It is a semi-synthetic, broad-spectrum, and third-generation cephalosporin compound with antibiotic and bactericidal activities.

For studying the expression, binding, and inhibition of penicillin-binding proteins.Cefoperazone sodium salt is used in the study of drug-protein binding, expression and inhibition of penicillin-binding proteins during cell wall synthesis. It is as an antibacterial and antimicrobial agent useful for prevention of postoperative infection. It is used as an inhibitor of inactivation of alfa-antitrypsin.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Cefoperazone sodium salt is a semi-synthetic, broad-spectrum, third-generation cephalosporin compound with antibiotic and bactericidal activities
• This compound can inhibit bacterial cell wall synthesis by inactivating penicillin-binding proteins and consequently interfering with the final transpeptidation step required for cross-linking peptidoglycan units, an important component of bacterial cell walls. This leads to a reduction in cell wall stability, causing cell lysis

Application

• Cefoperazone sodium salt exhibits activity against β-lactamase resistant microorganisms
• This compound is also used for studying the expression, binding, and inhibition of penicillin-binding proteins
• Cefoperazone is active in vitro against most gram-positive and gram-negative bacteria, including β-lactamase strains
• This compound has the ability to inhibit ∝-antitrypsin

Specifications

• Type: Cefoperazone Sodium Salt
• Physical Form: Powder
• Beilstein: 4902135
• Merck Index: 14,1930
• Solubility Information: Soluble in water; Slightly soluble in alcohol.
• Formula Weight: 667.65
• Color: White
• Quantity: 1 g
• Chemical Name or Material: Cefoperazone sodium salt

Safety and Handling

Hazard Category	H317-H334
Hazard Statement	GHS H Statement H334-H317 May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction.
Precautionary Statement	GHS P Statement P284a-P261-P280-P342+P311-P363-P501a Avoid breathing dust/fume/gas/mist/vapors/spray. Wear protective gloves/protective clothing/eye protection/face protection. If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Dispose of contents/container in accordance with local/regional/national/international regulations.
EINECSNumber	263-751-5
RTECSNumber	XI0374000
TSCA	No
Recommended Storage	Keep cold

SDS

RUO – Research Use Only