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  6. Cefotaxime sodium salt, Thermo Scientific Chemicals

Cefotaxime sodium salt, Thermo Scientific Chemicals

Catalog Number aaj6269003
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Quantity:
1 g
5 g
25 g
64485-93-4
C16H16N5NaO7S2
477.44
MFCD00079073
AZZMGZXNTDTSME-JUZDKLSSSA-M
88631411
sodium (6R,7R)-3-[(acetyloxy)methyl]-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
[Na+].CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(C)=O)=C(N2C1=O)C([O-])=O)C1=CSC(N)=N1
64485-93-4
C16H16N5NaO7S2
477.44
MFCD00079073
AZZMGZXNTDTSME-JUZDKLSSSA-M
88631411
sodium (6R,7R)-3-[(acetyloxy)methyl]-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
[Na+].CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(C)=O)=C(N2C1=O)C([O-])=O)C1=CSC(N)=N1

Description

Cefotaxime sodium salt, CAS # 64485-93-4, is the sodium salt form of cefotaxime with β-lactamase resistant antibiotic activity.

Cefotaxime sodium salt acts as a beta-lactamase resistant antibiotic. It is used as an effective antibacterial against gram-negative bacteria, with the notable exception of pseudomonas and penicillin-resistant strains of streptococcus pneumoniae. It is used to treat infections of the bones, joints, skin, respiratory tract and blood stream.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Information

• The cefotaxime sodium salt is a - lactamase considered a third-generation cephalosporin with antibiotic and bactericidal activities
• This compound exerts its biological activity by binding to penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall leading to their inactivation. The inactivation of these proteins affects the cross-linking of peptidoglycan chains required for bacterial cell wall strength and rigidity, resulting in the weakening of cell walls and cell lysis.

Applications

• It is an efficient antibacterial compound that acts against gram-negative bacteria, without activity against gram-positive bacteria such as pseudomonas and penicillin-resistant strains of streptococcus pneumonia
• It has been used for plant cell culture and human cell lines in vitro
• Cefotaxime sodium salt has been used in antibiotic susceptibility testing (AST) methods
• Cefotaxime sodium salt is also used to remove bacteria from Ostreococcus tauri cultures

TRUSTED_SUSTAINABILITY
Type Cefotaxime Sodium Salt
Physical Form Powder
Beilstein 5711411
Merck Index 14,1933
Solubility Information Soluble in water.
Formula Weight 477.4
Color White to Yellow
Quantity 1 g
Chemical Name or Material Cefotaxime sodium salt

Safety and Handling

Hazard Category H315-H317-H319-H334-H335
Hazard Statement GHS H Statement
H334-H317
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
May cause an allergic skin reaction.
Precautionary Statement P260-P264b-P271-P272-P280-P285-P302+P352-P304+P340-P305+P351+P338-P314-P333+P313-P342+P311-P362-P501c
EINECSNumber 264-915-9
RTECSNumber XI0250000
TSCA No
Recommended Storage Ambient temperatures
SDS

RUO – Research Use Only

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