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CELSR2 Rabbit anti-Human, Rat, Polyclonal, Invitrogen

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550591

Catalog No. PA550591


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Description

Description

The antibody detects endogenous levels of total CELSR2 protein.

The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined.
Specifications

Specifications

CELSR2
Polyclonal
Unconjugated
CELSR2
Liquid
CELSR2
Synthetic peptide corresponding to a region derived from internal residues of human cadherin, EGF LAG seven-pass G-type receptor 2
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Rat
Immunohistochemistry (Paraffin)
1.6 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
Q9HCU4, Q9QYP2
CDHF10, EGFL2, FLJ34118, FLJ42737, FLJ45143, FLJ45845, Flamingo1, KIAA0279, MEGF3
Rabbit
IgG
100 μL
-20°C
Primary
1952, 83465
Documents
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